Expanding a lymph node, boosting a vaccine

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Expanding a lymph node, boosting a vaccine

Researchers have found a way to enhance and extend LN expansion, and study how this phenomenon affects both the immune system and efficacy of vaccinations against tumors. While the oversized LNs maintained a normal tissue organization, they displayed altered mechanical features and hosted higher numbers of various immune cell types that commonly are involved in immune responses against pathogens and cancers. Importantly, 'jump-starting' lymph no…