Published 17 days ago

Genetic adaptations have impacted the blood compositions of two populations from Papua New Guinea, finds study

Summary by Phys.org

Papua New Guinea (PNG) has a wide range of environments, each presenting unique challenges to human survival. Highlanders and lowlanders of PNG are striking examples of populations facing distinct environmental stress. Whereas the highlanders encounter low oxygen availability due to altitude, the lowlanders are exposed to specific pathogens that are absent in the highlands, such as malaria. Despite these strong environmental pressures, the speci…

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Phys.org

Genetic adaptations have impacted the blood compositions of two populations from Papua New Guinea, finds study

17 days ago·United Kingdom

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Nature

Positive selection in the genomes of two Papua New Guinean populations at distinct altitude levels

Highlanders and lowlanders of Papua New Guinea have faced distinct environmental stress, such as hypoxia and environment-specific pathogen exposure, respectively. In this study, we explored the top genomics regions and the candidate driver SNPs for selection in these two populations using newly sequenced whole-genomes of 54 highlanders and 74 lowlanders. We identified two candidate SNPs under selection - one in highlanders, associated with red b…

17 days ago·United Kingdom

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Genetic adaptations have impacted the blood compositions of two populations from Papua New Guinea, finds study

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Genetic adaptations have impacted the blood compositions of two populations from Papua New Guinea, finds study

Genetic adaptations have impacted the blood compositions of two populations from Papua New Guinea, finds study

Positive selection in the genomes of two Papua New Guinean populations at distinct altitude levels

Positive selection in the genomes of two Papua New Guinean populations at distinct altitude levels

Coverage Details

Bias Distribution

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