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ActivismScientists are increasingly joining environmental movements. As knowledge producers and influential figures in society, scientists are uniquely positioned to drive change. Here we explore how scientist identity shapes engagement in environmental activism using qualitative and quantitative data from a multinational survey of 329 scientists from 41 countries. Scientist identity content, specifically perception of the science-activism relationship,…See the Story
Scientists’ identities shape engagement with environmental activism
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Genome organization around nuclear speckles drives mRNA splicing efficiency
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Andrew M. Weiner (1958–2024)
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PsychedelicsPsychedelic substances such as lysergic acid diethylamide (LSD) and psilocybin show potential for the treatment of various neuropsychiatric disorders1–3. These compounds are thought to mediate their hallucinogenic and therapeutic effects through the serotonin (5-hydroxytryptamine (5-HT)) receptor 5-HT2A (ref. 4). However, 5-HT1A also plays a part in the behavioural effects of tryptamine hallucinogens5, particularly 5-methoxy-N,N-dimethyltryptami…See the Story
Structural pharmacology and therapeutic potential of 5-methoxytryptamines
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Menlo Park · Menlo ParkA boson sampler implements a restricted model of quantum computing. It is defined by the ability to sample from the distribution resulting from the interference of identical bosons propagating according to programmable, non-interacting dynamics1. An efficient exact classical simulation of boson sampling is not believed to exist, which has motivated ground-breaking boson sampling experiments in photonics with increasingly many photons2–12. Howeve…See the Story
An atomic boson sampler
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CancerAngiogenin, an RNase A-family protein, promotes angiogenesis and has been implicated in cancer, neurodegenerative diseases, and epigenetic inheritance 1-10. Upon activation during cellular stress, angiogenin cleaves tRNAs at the anticodon loop, resulting in translation repression 11-15. The catalytic activity of isolated angiogenin, however, is very low, and the mechanisms of the enzyme activation and tRNA specificity have remained a puzzle 3,16…See the Story
Structural mechanism of angiogenin activation by the ribosome
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VapingVaping involves the heating of chemical solutions (e-liquids) to high temperatures prior to lung inhalation. A risk exists that these chemicals undergo thermal decomposition to new chemical entities, the composition and health implications of which are largely unknown. To address this concern, a graph-convolutional neural network (NN) model was used to predict pyrolysis reactivity of 180 e-liquid chemical flavours. The output of this supervised …See the Story
Forecasting vaping health risks through neural network model prediction of flavour pyrolysis reactions
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